paraneoplastic syndrome 

today I’m going to talk about paraneoplastic syndrome because one of our girl really ask me about that.

First of all we need little explanation about that,

Wiki says like that

A paraneoplastic syndrome is a disease or symptom that is the consequence of the presence of cancer in the body, but is not due to the local presence of cancer cells.These phenomena are mediated by humoral factors (by hormones or cytokines) excreted by tumor cells or by an immune response against the tumor. 

Paraneoplastic syndromes are typical among middle aged to older patients, and they most commonly present with cancers of the lung, breast, ovaries or lymphatic system (a lymphoma).Sometimes the symptoms of paraneoplastic syndromes show before the diagnosis of a malignancy, which has been hypothesized to relate to the disease pathogenesis

Yes it is.

So they have different set of symptoms which is related to hormone hypersecretion

You can find it from a text book

So my description basically depends on diagnosis of itFor an example we can take a patient who is having hyperparathyroidism. So we have to exclude the other causes of hyperparathyroidism see hyperparathyroidismIf there is hyperparathyroidism which is related to the gland, biochemical investigation reveals the state of hormone levels and the state of gland if there is cancer in gland itself we can diagnosis it by doing imagine techniques.

If hormone levels are altered and gland is normal at that time we have to exclude the primary cases and investigate for other causes. In that case we can investigate for parathyroid related peptide, CXR, CT chest, CT abdomen etc. and we have to find the primary tumour, then do histology and confirm the diagnosis.Finally we can start treatments.

I will post another letter about Parathyroid disorders